August 2013

Awair: Breathe Better Technology

Stage 2 E-Team Grantees

Recipient Institution: 
Stanford University
Principal Investigator: 
Paul Yock
Grant Amount: 
$20,000
Year: 
2013

A device that reduces the pain and discomfort of an endotracheal tube by applying local anesthetic (lidocaine) directly to the airway.

See the video here:
http://vimeo.com/63435122



The team:
 AWAIR: Breathe Better Technology – Awarded $20,000

The team members:

  • Rush Bartlett II, Ph.D., MBA, 2012-13 Cottrell Specialty fellow in Stanford Biodesign; co-founder of LyoGo and LEMM Technologies
  • Ryan Van Wert, M.D., 2012-13 Cottrell Specialty fellow in Stanford Biodesign; post-doctoral fellow in Pulmonary and Critical Care Medicine

Principal Investigator:
Paul Yock, MD, Martha Meier Weiland Professor of Medicine
Director, Biodesign

School: 
Stanford University

The innovation: 

The Wyshbone drug delivery catheter, which continuously applies topical anesthetic to the throat to reduce endotracheal (breathing) tube insertion discomfort.

The problem: 
Intensive Care Unit (ICU) patients on a ventilator require a painful endotracheal breathing tube to be placed in the throat, necessitating powerful intravenous sedatives (IVS) to mask the pain, which can lead to a number of negative side effects. When compared with ICU patients who do not have breathing tubes and are not heavily sedated, the breathing tube patients often have longer hospital stays and are more likely to develop ventilator-associated pneumonia, deep vein thrombosis, pressure ulcers and delirium. This demonstrates a need to eliminate or reduce sedation for people with breathing tubes.

The solution: 

Rush and Ryan created the Wyshbone drug delivery catheter, a device that continuously applies lidocaine, a topical painkiller, to the throat in order to reduce the discomfort of having a breathing tube inserted. AWAIR’s targeted approach helps clinicians to minimize the use of IVS and allows the patient to be awake and comfortable during the process. In pilot studies, the Wyshbone catheter reduces the use of IVS by half. Wyshbone is the first device to deliver continuous lidocaine to the airway.

The future:
AWAIR is currently working to perfect the Wyshbone prototypes. The team plans to garner user feedback on the prototypes by piloting the technology in multiple academic centers throughout the U.S. and Canada. Wyshbone has a strong intellectual property position and requires low-risk trials such as these to receive regulatory approval. If the user feedback and testing results are positive, AWAIR will continue to raise funding for regulatory approval and eventually production.

Tip for student innovators:

Ryan advises collegiate innovators to “listen, be intellectually honest and persevere.”

Acomni, LLC

Stage 1 E-Team Grantees

Recipient Institution: 
University of Arizona
Principal Investigator: 
Susan Lysecky
Grant Amount: 
$5,000
Year: 
2013

A thermostat monitor able to learn the characteristics of each house and, based on the weather forecast and a user-defined schedule, provide up-to-date energy usage and cost predictions and make recommendations.

Trash 2 Cash-Energy

Stage 1 E-Team Grantees

Recipient Institution: 
University of South Florida
Principal Investigator: 
John Kuhn
Grant Amount: 
$5,000
Year: 
2013

A catalytic process that turns an environmentally harmful byproduct of decaying garbage into fuel that could powers the fleet of garbage trucks.

Effuelent

Stage 1 E-Team Grantees

Recipient Institution: 
University of Cincinnati
Principal Investigator: 
Charles Matthews
Grant Amount: 
$5,000
Year: 
2013

A new technology able to separate fats, oils and greases, useful as biodiesel feedstocks, from trap grease sourced directly from the traps and from skimmers in wastewater treatment plants.

HMSolution

Stage 1 E-Team Grantees

Recipient Institution: 
Brown University
Principal Investigator: 
Angus Kingon
Grant Amount: 
$5,000
Year: 
2013

A water filtration system that reduces arsenic and heavy metals concentrations to safe levels and requires little to no maintenance for 10+ years.

The MadiDrop: A novel means to provide simple, safe & affordable drinking water

Stage 1 E-Team Grantees

Recipient Institution: 
University of Virginia
Principal Investigator: 
James Smith
Grant Amount: 
$5,000
Year: 
2013

A new point-of-use water filtering technology for the developing world that consists of a porous ceramic disk that releases silver at a controlled rate, eliminating microbial pathogens.

NutrAssess Technologies

Stage 1 E-Team Grantees

Recipient Institution: 
Johns Hopkins University
Principal Investigator: 
Youseph Yazdi
Grant Amount: 
$5,000
Year: 
2013

A mobile-phone-driven device that rapidly assesses childhood malnutrition in the developing world.

Fostail BioSystems LLC

Stage 1 E-Team Grantees

Recipient Institution: 
University of Idaho
Principal Investigator: 
Jon Van Gerpen
Grant Amount: 
$5,000
Year: 
2013

A new technology that significantly improves the production of ethanol by reducing fermentation time from days to hours and increasing ethanol yield by 5%.

iCRAFT

Stage 1 E-Team Grantees

Recipient Institution: 
Northeastern University
Principal Investigator: 
Waleed Meleis
Grant Amount: 
$5,000
Year: 
2013

A robotic arm for quadriplegics or other people unable to feed themselves that allows the user to select items using his or her eyes and return them to the table in real time.

SmarTummy: A Dynamic Abdominal Examination Simulator

Stage 1 E-Team Grantees

Recipient Institution: 
University of Hawaii at Manoa
Principal Investigator: 
Scott Miller
Grant Amount: 
$5,000
Year: 
2013

A training device, designed for medical students learning how to conduct an abdominal palpation exam, which consists of a manikin torso embedded with a series of inflatables that replicate the tactile feel of a variety of abdominal ailments.