Rotavirus Vaccination via Oral Thin Film Delivery

Johns Hopkins University, 2006 - $16,000

Rotavirus, a disease affecting children age five and younger, kills 600,000 people every year in the developing world. The virus infects the villi of the small intestines, leading to severe diarrhea, vomiting, high fever and dehydration. While rotavirus vaccines exist, they are currently delivered only in liquid form in a syringe, making the vaccine difficult to administer to infants and requiring expensive refrigeration to maintain. Building on thin film technology such as the popular Listerine Breath Strips, this E-Team is developing a method of delivering a rotavirus vaccine orally, on thin film. The team believes this design will have many advantages over current syringe-based methods, including simplifying storage and distribution due to the film's light weight and ability to be stored without refrigeration, and easier delivery to infants.

Above photo by Will Kirk.

Update: