pacemakers

BioTrace

Stanford University, 2010 - $20,000

Cardiac pacemakers save lives by restoring and maintaining a normal, safe heart rate for patients with heart rhythm disorders such as bradycardia (a pathologically slow heart rate). But despite their effectiveness, most patients with bradycardia do not need a permanent implanted device because their problem is temporary and reversible: the heart rhythm disruption stems from a procedure or as a side effect of medication. The options for short-term, temporary pacing to overcome bradycardia are, however, flawed: intravenous medications work only for a subset of patients and have limiting side effects; external pacing pads placed on the chest are ineffective and prohibitively painful to the patient. The placement of a temporary pacing electrode through a large vein directly into the heart is the most effective method, but, unfortunately, it is also known to cause potentially fatal complications, including perforation of the heart wall (1-2%) and dislodgement (10-30%).

To meet the need for a safer method of temporarily supporting patients who have or are at risk for bradycardia, this E-Team is developing a temporary pacing system that eliminates the majority of adverse events due either to perforation or dislodgement.

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